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Hi, T erri
Since this also happens in brand-new workbooks, I would not treat this as file corruption. It sounds more like Excel for Mac is losing its copy state, or the Home ribbon is not refreshing correctly after the first paste.
Besides the solutions provided by the Q&A Assist, here are some suggestions you can try:
First, check whether Cmd+V or Edit > Paste still works when the ribbon Paste button is greyed out. If it does, the issue is likely with the ribbon display, not the actual paste feature.
It is suggested that you reset the Excel ribbon settings: go to Excel > Preferences > Ribbon & Toolbar, then reset the ribbon/customizations. After that, fully quit Excel and reopen it.
Also try pressing Esc, then copy the row again and select the destination cell with a single click only. If Excel thinks you are editing inside a cell, paste controls can become unavailable.
If it still happens, create a new macOS user account and test Excel there. If paste works normally there, the problem is probably in the current Mac user profile or Excel preferences, not your workbooks. At that point, I’d go back to Microsoft Support with both service request numbers and mention that the issue started after the updater file.
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Thank you for your patience in reading, I hope this information has been helpful to you.
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