Hello @romibi
The behavior does appear consistent with a regression introduced after KB5121003, especially if multi-monitor RDP works normally immediately after uninstalling the update and fails again when it is reinstalled.
KB5121003 is the August 11, 2026 cumulative security update for Windows 11 24H2/25H2 (OS Builds 26100.9168 / 26200.9168).
However, as of Microsoft's current documentation, RDP multi-monitor failure is not listed as a confirmed known issue for KB5121003. The currently documented issue involves certain games and RGB-related drivers.
Since you've already isolated the problem to the update, I would recommend:
- Confirm the affected client build with winver and test mstsc /multimon after installing and removing KB5121003.
- Check Event Viewer > Applications and Services Logs > Microsoft > Windows > TerminalServices-ClientActiveXCore for errors during the failed connection.
- Update the display/GPU drivers and test with different monitor arrangements/scaling values to rule out a display-driver interaction.
- Submit the reproduction through Feedback Hub (Win+F) and include the KB number, monitor topology/resolutions, GPU/driver version, RDP logs, and the fact that uninstalling KB5121003 restores functionality.
- In an enterprise environment, I'd also open a Microsoft support case so they can investigate the issue as a possible KB5121003 regression.
I would not recommend uninstalling KB5121003 as a permanent solution, since it's a security cumulative update. If removing it is the only working mitigation, use that only temporarily while Microsoft investigates or until a subsequent cumulative update resolves the behavior.
Sharing these references with you:
KB5121003 - August 11, 2026 Windows 11 update
Windows 11 24H2 known issues and notifications
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